ReviewMedicine2026
Inflammation at the crossroads: A bibliometric and integrative review of metabolic-cardiac links in diabetic cardiomyopathy (2004-2024).
Review in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Pulsatility as a Potential Regulator of Cardiovascular Biology: Molecular, Cellular, and Hemodynamic Remodeling During Continuous-Flow Left Ventricular Assist Device Support and Following Heart Transplantation.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic cardiomyopathy (DCM) is a significant diabetes complication, primarily due to persistently high blood sugar and metabolic issues. Chronic low-grade inflammation plays a key role in its development and is closely associated with cardiomyocyte damage and the progression of heart failure. With diabetes being widespread, DCM greatly raises cardiovascular mortality risk. There's increasing interest in targeting inflammation-related metabolic immune dysregulation to treat DCM. However, current bibliometric analyses are outdated and need updating. This study aims to provide a comprehensive review of recent developments and trends in inflammation's role in DCM, enhancing researchers' understanding and guiding future research.
methodsSearched the core Web of Science databases. EndNote 21, Microsoft Excel 365, CiteSpace, VOSviewer, and SCImago Graphica were used to explore current research trends and shifts in hotspots.
resultsFrom 2004 to 2024, 818 publications were analyzed. Annual publications surged significantly after 2016, peaking in 2024 (n > 100). China (n = 508) and the USA (n = 135) were the most productive countries. Wenzhou Medical University was the leading institution. Keyword analysis identified "DCM," "oxidative stress," "inflammation," "heart failure," and "mechanisms" as core themes, with recent emphasis on pathways linking metabolic dysfunction, inflammation, and structural/functional cardiac abnormalities. "Preserved ejection fraction" emerged as a recent burst keyword.
conclusionThis bibliometric analysis of inflammation in DCM highlights a rapidly expanding field, primarily led by China and the US. Key insights include the central role of oxidative stress-inflammation and metabolic dysregulation, with a new emphasis on HFpEF since 2021. Researchers should focus on multi-organ inflammatory networks and targeted anti-inflammatory treatments, while clinicians should adopt personalized strategies to prevent disease progression. This study addresses crucial gaps to lessen the cardiovascular impact of diabetes.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.