Evidence map›Paper›PMID 42470601›Full record

ReviewAdvances in therapy2026

Expert Consensus on the Clinical Application of Sulodexide in Vascular Diseases.

Yongjun Li, Yu Zhao, Wei Ye, Consensus Working Group of the Vascular Surgery Branch of the China International Exchange and Promotive Association for Medical and Health Care, the Geriatric Pharmacy Professional Committee of the China Medical Education Association, and the Vascular Limb Salvage Branch of the Beijing Association of Holistic Integrative Medicine

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Advances in therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yongjun LiBeijing Hospital, National Center of Gerontology, No. 1 Dondan Dahua Road, Dongcheng District, Beijing, China. liyongjun4679@bjhmoh.cn.
Yu ZhaoThe First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuanjiagang, Yuzhong District, Chongqing, China.
Wei YePeking Union Medical College Hospital, No.1 Shuai Fu Yuan, Dongcheng District, Beijing, China.
Consensus Working Group of the Vascular Surgery Branch of the China International Exchange and Promotive Association for Medical and Health Care, the Geriatric Pharmacy Professional Committee of the China Medical Education Association, and the Vascular Limb Salvage Branch of the Beijing Association of Holistic Integrative Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sulodexide is a highly purified glycosaminoglycan with multiple pharmacological effects, including endothelial glycocalyx repair, endothelial cell protection, anti-inflammatory and antithrombotic actions, promotion of fibrinolysis, reduction of blood viscosity, lipid regulation, and anti-oxidative activity. It serves as a potentially effective foundational therapeutic agent for the prevention and treatment of vascular diseases. This consensus integrates current scientific knowledge on the clinical application of sulodexide in vascular diseases, aiming to provide guidance and reference for rational drug use among clinicians. The consensus statements first elaborate on the pharmacological mechanisms and pharmacokinetic profiles of sulodexide. Through a structured review and integration of published basic and clinical research evidence from China and abroad, it summarizes clinical efficacy and safety data for sulodexide in chronic venous disease, venous thromboembolism, peripheral arterial disease, and microangiopathy, highlighting the importance of rational use of sulodexide in vascular disease management. Additionally, based on evidence-based medicine and existing medical guidelines, specific clinical application recommendations are proposed.

Indexed as

Anti-inflammatoryAntithromboticChronic venous diseaseClinical applicationConsensus developmentDiabetic nephropathyPeripheral arterial diseaseSulodexideVascular diseaseVenous thromboembolism

Identifiers

PMID42470601

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.