ArticleInternational journal of cardiology. Cardiovascular risk and prevention2026
Health-related quality of life after acute myocardial infarction and one-year clinical outcomes: A prospective cohort study.
Article in International journal of cardiology. Cardiovascular risk and prevention, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Acute myocardial infarction (AMI) remains a leading cause of death worldwide and in Colombia. Beyond survival, AMI can markedly impair health-related quality of life (HRQoL), yet the prognostic value of HRQoL measured during the index hospitalization remains insufficiently explored, particularly in middle-income countries. Methods: We conducted a prospective cohort study of 1093 adults with type 1 myocardial infarction admitted to a tertiary referral center in Colombia between 2023 and 2025. HRQoL was assessed within 24 h of admission using the EuroQol 5-Dimension 3-Level (EQ-5D-3L) instrument and the EuroQol Visual Analogue Scale (EQ-VAS). Multivariable Poisson regression with robust variance was used to estimate adjusted risk ratios (RRs) for one-year mortality and rehospitalization. Results: At 12 months, all-cause mortality was 4.3% and rehospitalization was 2.6%. Impairment in the mobility domain was independently associated with higher risks of mortality (RR = 1.80; p = 0.045) and rehospitalization (RR = 2.22; p = 0.031). Percutaneous coronary intervention (RR = 0.28; p < 0.001) and male sex (RR = 0.54; p = 0.034) were associated with lower mortality risk. Conclusion: Baseline HRQoL assessed during hospitalization for AMI was associated with one-year mortality and rehospitalization. Mobility limitations identified patients at higher risk and may complement conventional clinical risk stratification.
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