ArticleCureus2026
Outcomes of Radiocephalic Arteriovenous Fistulas (RC-AVFs) in Patients Aged ≥70 Years: The Impact of Frailty on Maturation and Patency.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Background Radiocephalic arteriovenous fistulas (RC-AVFs) are preferred for hemodialysis access, but outcomes in elderly patients remain debated. Frailty may influence maturation and patency. Methods This was a retrospective cohort study of patients aged ≥70 years who underwent RC-AVF creation over a 12-month period at a single center. Frailty was assessed using the Clinical Frailty Scale (CFS) and categorized as frail (CFS ≥5) or non-frail (CFS ≤4). The primary outcome was primary failure (failure to achieve functional hemodialysis use during follow-up). Secondary outcomes included patency at three, six, and 12 months and the need for intervention. Logistic regression was used to assess the association between CFS (per one-point increase) and primary failure. Results A total of 52 patients were included (mean age: 75.9 years; 38 {73.1%} male). Primary failure occurred in 23 (44.2%) patients. Frail patients had higher rates of primary failure than non-frail patients (12/20 {60.0%} vs. 11/32 {34.4%}, p=0.090). Each one-point increase in CFS was associated with increased odds of primary failure (OR: 1.87, p=0.013). Patency at three, six, and 12 months was 44 (84.6%), 39 (75.0%), and 29 (55.8%), respectively; 12-month patency was lower in frail patients (4/11 {36.4%} vs. 12/18 {66.7%}, p=0.143). Interventions were required in 17 (32.7%) patients, most commonly angioplasty. Conclusions Frailty was strongly associated with primary failure after RC-AVF creation in patients aged ≥70 years. Incorporating frailty assessment into preoperative evaluation may improve patient selection and counseling, and support shared decision-making.
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