Evidence map›Paper›PMID 42473633›Full record

ArticleObesity science & practice2026

Optimizing Goal Difficulty in a Digital Weight Loss Intervention: The Ignite Pilot Randomized Trial.

Michele L Patel, John A Gallis, Amanda B Zeitlin, Phoebe C Crosthwaite, Annalisa W Lim, Kayla A Collins, Marily A Oppezzo, Lisa G Rosas

Registry-linked trialAbstract read
In one paragraph

Article in Obesity science & practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05715242 (Goal Setting in a Standalone, Digital Weight Loss Intervention), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05715242 nacompletednot on this map

Goal Setting in a Standalone, Digital Weight Loss Intervention: a Pilot Factorial Trial

TypeinterventionalSponsorStanford UniversityRan2023 to 2024Enrolled32ConditionsObesity, Overweight, Weight Loss, Health BehaviorArmsCore Behavioral Weight Loss Intervention, Easier Step Goal, Harder Step Goal, Easier Calorie Goal, Harder Calorie Goal
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michele L PatelStanford Prevention Research Center, Department of Medicine Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0000-0001-5307-4861
John A GallisDuke Global Health Institute, Duke University Durham North Carolina USA.ORCID https://orcid.org/0000-0003-1921-8424
Amanda B ZeitlinStanford Prevention Research Center, Department of Medicine Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0009-0005-1822-8198
Phoebe C CrosthwaiteStanford Prevention Research Center, Department of Medicine Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0009-0005-2167-691X
Annalisa W LimStanford University Stanford California USA.ORCID https://orcid.org/0009-0001-6214-6908
Kayla A CollinsStanford University Stanford California USA.ORCID https://orcid.org/0009-0000-5537-0277
Marily A OppezzoStanford Prevention Research Center, Department of Medicine Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0000-0001-6668-2508
Lisa G RosasDepartment of Epidemiology & Population Health Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0000-0003-4053-7972

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
Stanford Center for Clinical and Translational Research and EducationUM1TR004921 · NCATS · STANFORD UNIVERSITY · PI MANISHA DESAI, DEAN W FELSHER · 2024 to 2026
$30.1M
Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI HASSAN CHAIB · 2017 to 2026
$19.5M
Optimizing self-monitoring in a digital health intervention for weight lossK23DK129805 · NIDDK · STANFORD UNIVERSITY · PI Michele Lanpher Patel · 2022 to 2026
$970k
NCATS NIH HHS UL1 TR003142NCATS NIH HHS UM1 TR004921NIDDK NIH HHS K23 DK129805NIDDK NIH HHS P30 DK116074
6 · The paper itself

Abstract

Background: Goal setting is a key component in behavioral weight loss interventions. Goal setting theory emphasizes having harder goals rather than easier goals. However, few studies have experimentally manipulated goal difficulty levels in digital weight loss interventions. Further, when multiple goals are assigned, it is unclear if harder goals are effective or too overwhelming. Methods: Ignite was a pilot optimization trial guided by the Multiphase Optimization Strategy. A 2 Results: Participants had a mean (SD) age of 47.7 (13.3) years and BMI of 30.1 (3.8) kg/m Conclusion: With high feasibility of study procedures, high engagement, and moderate-to-high acceptability, the intervention needs only minor refinements prior to proceeding to a fully powered trial testing the efficacy of easier versus harder goals for weight loss. Trial Registration: ClinicalTrials.gov NCT05715242. Registered on February 6, 2023.

Indexed as

digital healthgoal settinglifestyle interventionMultiphase Optimization Strategyobesityweight loss

Identifiers

PMID42473633
PMCPMC13380974

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.