ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Family resilience clusters and quality of life in adolescents and young adults with cancer and their caregivers: a dyadic cluster analysis.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo identify dyadic patterns of family resilience among adolescents and young adults (AYAs) with cancer and their caregivers, and to explore associated factors and their relationships with quality of life (QoL) in both parties.
methodsThis cross-sectional study recruited 202 AYA patient-caregiver dyads from four tertiary hospitals in Wuhan and Taiyuan between July 2022 and March 2024. Data were collected through a self-designed general information questionnaire and validated instruments assessing family resilience, individual resilience, social support, and QoL. Family resilience clusters were identified using K-means clustering in R 4.4.3, followed by regression analyses in SPSS 20.0.
resultsTwo family resilience clusters were identified: the low and high family resilience clusters. High resilience clusters were characterized by having an only child, a shorter disease course (1 ~ 3 months), having a smaller family size (≤ 3 family members), and shorter daily caregiving hours. Caregiver QoL was associated with family resilience cluster, caregiver employment changes, and social support, whereas patient QoL was primarily influenced by their individual resilience.
conclusionsThis study identified heterogeneity in family resilience among AYA patient-caregiver dyads, with smaller family size, a shorter disease course, and shorter caregiving hours associated with membership in the high resilience cluster. Caregiver well-being was closely linked to family resilience and social-contextual factors, while patient QoL depended more on individual resilience. These findings advance understanding of family resilience in AYA oncology and underscore the importance of family-centered psychosocial support to strengthen family functioning, alleviate caregiver burden, and foster patient resilience.
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