Evidence map›Paper›PMID 42474921›Full record

ArticleOdontology2026

Effectiveness of photobiomodulation in the treatment of xerostomia in type II diabetic patients.

Heba A Ali, Nahed S Attia, Azza M Zaki, Yasmine Y Gaweesh

Registry-linked trialAbstract read
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In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06703372 (Effectiveness Of Photobiomodulation In Treatment Of Xerostomia In Type Ii Diabetic Patients), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06703372 nacompletednot on this map

Effectiveness Of Photobiomodulation In Treatment Of Xerostomia In Type Ii Diabetic Patients (A Randomized, Controlled Clinical Trial)

TypeinterventionalSponsorHams Hamed AbdelrahmanRan2022 to 2024Enrolled60ConditionsXerostomia, Diabetes MellitusArmsDiode Laser 980 nm, 0.2W, Placebo Diode laser
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Heba A AliFaculty of Dentistry, Alexandria University, Champollion St, Azarita, Alexandria, Egypt.ORCID http://orcid.org/0009-0007-6391-9099
Nahed S AttiaFaculty of Dentistry, Alexandria University, Champollion St, Azarita, Alexandria, Egypt.
Azza M ZakiFaculty of Dentistry, Alexandria University, Champollion St, Azarita, Alexandria, Egypt.
Yasmine Y GaweeshFaculty of Dentistry, Alexandria University, Champollion St, Azarita, Alexandria, Egypt. yasmine.gaweesh@alexu.edu.eg.ORCID http://orcid.org/0000-0001-6626-5966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the effect of diode laser photobiomodulation in the treatment of xerostomia among diabetics. A randomized controlled clinical trial was conducted on 52 diabetic patients experiencing xerostomia. Participants were randomly assigned to a test group, receiving diode laser application or to a control group, receiving no active treatment. Unstimulated and stimulated salivary flow rates were assessed at baseline, 2, 4, 6 and 12 weeks. Subjective xerostomia symptoms were evaluated using the Xerostomia Inventory. In the test group, unstimulated salivary flow rose from 0.13 ± 0.04 mL/min at baseline to 0.25 ± 0.06 at week 12, and stimulated flow from 0.51 ± 0.09 to 1.00 ± 0.27 (p < 0.001 for both). Unstimulated flow in the control group increased from 0.12 ± 0.05 to 0.14 ± 0.05, and stimulated flow from 0.48 ± 0.10 to 0.54 ± 0.11, with significance detected only at week 12. Subjective xerostomia scores also improved in the test group, decreasing from 12.19 ± 2.02 to 8.48 ± 1.83 (p < 0.001), while no significant change was noted in the control group. Photobiomodulation with a 980 nm diode laser might be an effective and safe therapeutic modality to improve salivary flow and xerostomia symptoms in diabetic patients.Trial registration:The study has been registered at ClinicalTrials.gov (NCT06703372), 22/11 2024.

Indexed as

DiabetesPhotobiomodulationSalivary flowXerostomia

Identifiers

What Socratic holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.