ReviewNpj biological timing and sleep2026
Theoretical chronobiology of circadian timing-gold mine or minefield?
Review in Npj biological timing and sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
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Abstract
From noisy single cells to coupled tissues, circadian rhythms depend on interactions across multiple scales and on external time cues. Oscillator theory has played a central role in making sense of these dynamics, particularly in explaining synchronization and entrainment. Yet the same abstractions that make oscillator models powerful can also mask biologically relevant differences between systems. In this perspective, we outline where oscillator theory has been most informative, where it can mislead, and what this means for future experimental and theoretical work. While we focus here on circadian rhythms, related principles extend to other biological oscillators across timescales.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.