Evidence map›Paper›PMID 42477844›Full record

ArticleImplementation science communications2026

A co-creation approach to selecting and adapting adolescent tobacco and air-pollution interventions and strategies for implementation in diverse countries: insights from FRESHAIR4Life.

Purva Abhyankar, Alexander Lepe, Jurjen van der Schans, Floor A van den Brand, Faraz Siddiqui, Saima Saeed, Javeria Akhter, Amina Khan, Mian Ali Kamran Baba, Ioanna Tsiligianni and 16 more

Abstract read
In one paragraph

Article in Implementation science communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Purva AbhyankarUsher Institute, University of Edinburgh, 5‒7 Little France Road, Edinburgh BioQuarter ‒ Gate 3, Edinburgh, UK. pabhyank@ed.ac.uk.ORCID http://orcid.org/0000-0002-0779-6588
Alexander LepeGlobal Health Unit, Department of Health Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Jurjen van der SchansGlobal Health Unit, Department of Health Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Floor A van den BrandDepartment of Family Medicine (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Faraz SiddiquiDepartment of Health Sciences, University of York, York, UK.
Saima SaeedIndus Hospital and Health Network, Karachi, Pakistan.
Javeria AkhterIndus Hospital and Health Network, Karachi, Pakistan.
Amina KhanThe Initiative, Islamabad, Pakistan.
Mian Ali Kamran BabaThe Initiative, Islamabad, Pakistan.
Ioanna TsiligianniDepartment of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Izolde BouloukakiDepartment of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Antonios ChristodoulakisDepartment of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Winceslaus KatagiraCollege of Health Sciences, Makerere University Lung Institute, Makerere University, Kampala, Uganda.
Bruce KirengaCollege of Health Sciences, Makerere University Lung Institute, Makerere University, Kampala, Uganda.
Cristina IsarCentrul National de Studii pentru Medicina Familiei (CNSMF RespiRO), Bucharest, Romania.
Adriana AntoheCentrul National de Studii pentru Medicina Familiei (CNSMF RespiRO), Bucharest, Romania.
Anca LupuCentrul National de Studii pentru Medicina Familiei (CNSMF RespiRO), Bucharest, Romania.
Andrea NeculauUniversitatea Transilvania, Brasov, Romania.
Talant SooronbaevDepartment of Pulmonology and Allergology, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, Bishkek, Kyrgyzstan.
Gulzada MirzalievaDepartment of Pulmonology and Allergology, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, Bishkek, Kyrgyzstan.
Aijan TaalaibekovaDepartment of Pulmonology and Allergology, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, Bishkek, Kyrgyzstan.
Rianne van der KleijLeiden University Medical Center, Public Health & Primary Care, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
D K ArvindCentre for Speckled Computing, School of Informatics, University of Edinburgh, Edinburgh, UK.
Siân WilliamsInternational Primary Care Respiratory Group (IPCRG), Edinburgh, UK.
Luís CarvalhoInternational Primary Care Respiratory Group (IPCRG), Edinburgh, UK.
Hilary PinnockUsher Institute, University of Edinburgh, 5‒7 Little France Road, Edinburgh BioQuarter ‒ Gate 3, Edinburgh, UK.

Funding

HORIZON EUROPE European Research Council 101095461
6 · The paper itself

Abstract

backgroundEvidence-based interventions to reduce adolescents' exposure to tobacco and air pollution are rarely implemented in low- and middle-income countries, often because they lack contextual fit. The 'FRESHAIR4Life' project aimed to optimise implementation of contextually adapted, evidence-based interventions in Greece, Kyrgyzstan, Pakistan, Romania, and Uganda. Selecting appropriate interventions required deliberate, inclusive, and context-sensitive decision-making. This paper outlines the co-creation approach for selecting and adapting interventions, developing implementation strategies and addressing the challenges that arose.

methodsEach country followed a four-step process. First, findings from local situational analyses were consolidated to identify barriers and facilitators across individual, community, and system levels and to map targets for change using the Theoretical Domains Framework. This was followed by a workshop with country-teams to identify key risk factors, target behaviours, relevant populations and settings, and to shortlist potential interventions from the FRESHAIR4Life palette alongside implementation strategies using option grids and ranking. A subsequent stakeholder workshop applied a Socio Technical Allocation of Resources informed approach to elicit perspectives on the interventions' value using qualitative (Conversation Café style discussions) and quantitative methods (ratings of need, importance, likely reach, feasibility, and local adaptations required, fixed budget allocation exercises or ranking of options). Finally, selection meetings with country teams finalised intervention choices and implementation strategies, informed by stakeholder input.

resultsCountries chose to target the risk factors that were considered most prevalent and the biggest threat to adolescent health in their settings. Of the four countries addressing tobacco use, Pakistan, Greece, and Romania selected 'implementation intentions (If-Then approach)' for prevention, while Kyrgyzstan selected 'very brief advice plus behavioural counselling (VBA+)' for cessation. All three countries addressing air pollution, Pakistan, Uganda and Kyrgyzstan selected social media campaigns. Key challenges included: (1) establishing a sound basis for selection decisions, which was overcome by adopting a systematic, transparent and inclusive decision process (2) ethical and practical considerations for addressing tobacco/nicotine use within school-based prevention, tackled by adapting intervention to include offer of cessation support (3) limited evidence-based interventions targeting ambient air pollution, addressed by flexibly moving beyond the palette (4) the evolving nature of implementation strategies and (5) embedding interventions into routine practice, both addressed through flexibility and adaptation.

conclusionThis study shows that, across diverse country contexts, defensible intervention selection depends not only on which intervention is chosen, but on how choices are made and by whom. A transparent, stakeholder-owned co-creation process, involving the target audience of adolescents, helped country teams navigate trade-offs between evidence, local burden, feasibility, fit with routine practice, and ethical obligations, while exposing important evidence gaps for individual- and community-level ambient air-pollution interventions in LMICs.

Indexed as

AdaptationAir pollutionCo-creationImplementation researchIntervention selectionNCD preventionNicotine useStakeholder involvementTobacco use

Identifiers

PMID42477844
PMCPMC13584592

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.