Evidence map›Paper›PMID 42478129›Full record

ArticleJournal of medical virology2026

Genetic Diversity and Genomic Characteristics of the Respiratory Virome in Patients With Severe Fungal Infections.

Yujing Zhou, Juan Xu, Wenxi Zhou, Ping Wu, Shixing Yang, Likai Ji, Quan Shen, Xiaochun Wang, Yuwei Liu, Chenglin Zhou and 2 more

Abstract read
In one paragraph

Article in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yujing ZhouDepartment of Gastroenterology, Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, Jiangsu, China.
Juan XuClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.
Wenxi ZhouDepartment of Gastroenterology, Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, Jiangsu, China.
Ping WuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Shixing YangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.ORCID https://orcid.org/0000-0001-9899-8291
Likai JiDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.ORCID https://orcid.org/0009-0007-0411-7774
Quan ShenDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Xiaochun WangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Yuwei LiuDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.ORCID https://orcid.org/0000-0002-5495-2926
Chenglin ZhouClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.ORCID https://orcid.org/0000-0003-2661-2067
Wen ZhangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.ORCID https://orcid.org/0000-0002-9352-6153
Min XuDepartment of Gastroenterology, Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, Jiangsu, China.ORCID https://orcid.org/0000-0002-5587-5520

Funding

National Key Research and Development Programs of China 2023YFD1801300National Natural Science Foundation of China 82341106National Natural Science Foundation of China 82550118Natural Science Foundation of Jiangsu Province BK20241926
6 · The paper itself

Abstract

Respiratory tract infections represent a leading cause of morbidity and mortality globally, with viral pathogens accounting for a substantial proportion of these cases. However, research on the human respiratory virome is still in its infancy, and our understanding of this field remains relatively limited. In the present study, viral metagenomic sequencing was conducted on 65 sputum samples obtained from patients with severe fungal infections. We successfully assembled viral genome sequences belonging to four distinct viral families: Anelloviridae, Genomoviridae, Microviridae, and Inoviridae. Through systematic analysis of the virome composition, this study characterized the structural features of the respiratory virome in patients with severe fungal infections. The findings provide a foundational description of viral diversity in this specific clinical context. These findings lay a theoretical foundation for clinical pathogen detection, targeted interventions, and the development of future prevention strategies.

Indexed as

Genetic VariationGenome, ViralMycosesRespiratory Tract InfectionsViromeVirusesAdultFemaleHumansMaleMetagenomicsMiddle AgedPhylogenySequence Analysis, DNASputumphylogenetic analysisrespiratory viromesevere fungal infectionviral diversityviral metagenomics

Identifiers

PMID42478129
PMCPMC13386028

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.