ReviewSports medicine - open2026
Distinct Movement-Related Cortical Control Following Anterior Cruciate Ligament Injury: A Scoping Review.
Review in Sports medicine - open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDistinct brain activity in anterior cruciate ligament (ACL) patients has been reported, yet comprehensive evidence on neural differences during movement and the potential impact on motor performance remains limited.
objectivesThis review aimed to synthesize evidence on cortical activity during motor tasks in ACL patients compared to healthy controls and explored the potential impact on motor performance.
methodsA scoping review was conducted in accordance with the Joanna Briggs Institute methodological guidance for scoping reviews and reported following the Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for scoping reviews. Eligible literature was searched in PubMed, Embase, SPORTDiscus, and Web of Science from inception to December 31, 2025, and included primary research assessing brain activity during voluntary motor tasks in ACL patients compared to controls.
resultsOut of 233 identified records, 25 were included, with 15 utilizing electroencephalography, 8 functional magnetic resonance imaging, and 2 functional near-infrared spectroscopy assessing a total of 416 ACL patients on study level. 21 studies reported significant between-group differences in brain activity, demonstrating increased activity in frontal and visual processing regions but inconsistent findings for motor and parietal cortices. Additionally, 14 records described behavioral data alongside neuroimaging results, of which 10 found no significant differences and 4 reported impaired motor performance.
conclusionDistinct patterns of brain activity were demonstrated in ACL patients compared to healthy controls, predominantly depicting increased recruitment of neural resources within the cognitive and visual network. Despite some evidence reporting associated impaired motor performance, the relationship between cortical alterations and motor performance remains hypothetical. Future research should incorporate paradigms including visual and cognitive dual-tasks to explore the relationship between brain activity and behavioral outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.