ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026
Oxygen cost of breathing and its association with dyspnea in older patients with heart failure with preserved ejection fraction and obesity.
Bryce N Balmain, Valentin Mons, Andrew R Tomlinson, James P MacNamara, Abidan Abulimiti, Michael G Leahy, Denis J Wakeham, Kevin Lutz, Linda S Hynan, Benjamin D Levine and 2 more
Abstract read
In one paragraphArticle in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
12 authors.
Bryce N BalmainInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-2642-7083 Valentin MonsInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Andrew R TomlinsonInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-9899-0812 James P MacNamaraInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0003-2795-6021 Abidan AbulimitiInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Michael G LeahyInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-9209-3982 Denis J WakehamInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-4200-3790 Kevin LutzDepartment of Health Data Science and Biostatistics, O'Donnell School of Public Health, University of Texas Southwestern Medical Center.ORCID 0000-0002-6687-0637 Linda S HynanDivision of Psychology, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-4642-7769 Benjamin D LevineInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-9064-7251 Satyam SarmaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-0628-4919 Tony G BabbInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-0515-2164 Funding
Targeting skeletal muscle to improve exercise capacity in heart failure with preserved ejection fraction.P01HL137630 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI TONY G BABB · 2022 to 2023
$9.1MHHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) K99HL164957HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) P01HL137630HHS | NIH | National Institute on Aging (NIA) R01AG070262NHLBI NIH HHS K99 HL164957NHLBI NIH HHS P01 HL137630NIA NIH HHS R01 AG070262
6 · The paper itselfAbstract
introductionObesity is associated with an increased oxygen (O
methodsWe evaluated 14 patients with HFpEF and obesity (HFpEF-Ob, BMI: 40.4±5.4 kg/m
resultsThe O2 cost of breathing was higher in HFpEF-Ob compared with CTL-nonOb (2.95±0.66 vs. 2.11±0.43mL/L, P=0.001) but was not different compared with CTL-Ob (2.48±0.73mL/L, P=0.130 vs. HFpEF-Ob). The rating of perceived breathlessness (RPB) was ≥1-unit higher in HFpEF-Ob, which is considered clinically significant. The O
conclusionThese findings suggest that the magnitude of obesity could increase the O
Indexed as
agingcost of breathingdyspneaHFpEFobesity
Identifiers
PMID42479445
PMCPMC13474405
What Socratic holds
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