Evidence map›Paper›PMID 42484328›Full record

ArticleJournal of virology2026

Extended hinge length of human IgG3-like antibody enhances early antiviral activity of VRC01 in SHIV-infected rhesus macaques.

Rhianna Jones, Cordelia Manickam, Sweta Shrestha, Kyle Kroll, Griffin Woolley, Maurice Bukenya, Derrick D Goodman, Katharine J Bar, Justin Pollara, Georgia D Tomaras and 3 more

Abstract readLetter
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rhianna Jones *Center for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Cordelia Manickam *Center for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Sweta ShresthaGeisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Kyle KrollCenter for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Griffin WoolleyCenter for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Maurice BukenyaCenter for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Derrick D GoodmanCenter for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Katharine J BarDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-9773-0071
Justin PollaraCenter for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Georgia D TomarasCenter for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Francois VillingerNew Iberia Primate Research Center, University of Louisiana at Lafayette, New Iberia, Louisiana, USA.
Margaret E AckermanGeisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.ORCID 0000-0002-4253-3476
R Keith ReevesCenter for Human Systems Immunology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0003-3157-2557

Funding

Structure-Function Analytics CoreP01AI162242 · NIAID · DUKE UNIVERSITY · PI TOMARAS, GEORGIA DORIS · 2021 to 2025
$22.2M
Mechanisms and means to improve HIV bnAb activity in vivoR01AI183970 · NIAID · DARTMOUTH COLLEGE · PI Margaret E Ackerman · 2024 to 2026
$2.5M
NIAID NIH HHS P01 AI162242NIAID NIH HHS R01 AI183970NIH HHS P01AI162242NIH HHS R01AI183970
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antibodyIgG3SHIVvirus decay

Identifiers

PMID42484328
PMCPMC13483424

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.