ReviewActa diabetologica2026
Micronutrients in immune ageing and diabetic wound healing: modulating inflammation and promoting tissue repair.
Review in Acta diabetologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune ageing, characterized by a decline in immune function and increased chronic inflammation, significantly impacts tissue repair mechanisms, particularly in diabetic wounds. Diabetic individuals often experience delayed wound healing due to impaired immune responses and persistent inflammation, making effective management of chronic wounds a challenge. Recent studies suggest that micronutrients, which play an essential role in modulating immune responses and inflammatory pathways, have the potential to mitigate these age-related dysfunctions and improve wound healing outcomes. This review explores key micronutrients, including Vitamin D, Vitamin C, Zinc, and Selenium, in enhancing immune function and promoting tissue repair in diabetic wound healing. We discuss how deficiencies in these micronutrients contribute to increased inflammation, delayed immune responses, and prolonged wound healing. Furthermore, we examine emerging micronutrients and their potential therapeutic benefits, such as Magnesium, Folic Acid, and Curcumin, in reducing oxidative stress and modulating immune function. In addition, innovative delivery systems, including liposomal encapsulation and nanotechnology, are highlighted as promising strategies to enhance the bioavailability and efficacy of micronutrients, ensuring their optimal therapeutic effect in ageing and diabetic populations. By synthesizing current evidence and proposing future research directions, this review emphasizes the importance of micronutrient supplementation as a therapeutic strategy to address immune ageing and accelerate wound healing, offering new opportunities for managing chronic diabetic wounds and related complications in the ageing population.
Indexed as
Identifiers
42484700What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.