Evidence map›Paper›PMID 42487929›Full record

ArticleFrontiers in chemistry2026

Synthesis, characterization, and

Abdelghani Sehmi, Farouk Boudou, Ahcene Keziz, Amal Belakredar, Huda Alsaeedi, Mikhael Bechelany, Gemma K Kinsella, Ahmed Barhoum

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In one paragraph

Article in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdelghani SehmiDepartment of Physical Science and Technology, Higher Normal School of Saida, Saïda, Algeria.
Farouk BoudouDepartment of Applied Molecular Genetics, Faculty of Natural and Life Sciences, University of Sciences and Technology of Oran, Mohamed-Boudiaf (USTO-MB), Oran, Algeria.
Ahcene KezizDepartment of Physics, and Chemistry of Materials Laboratory, University of M'sila, M'sila, Algeria.
Amal BelakredarDepartment of Biotechnology, Faculty of Natural Sciences and Life, University of Mostaganem Abdelhamid Ibn Badis, Mostaganem, Algeria.
Huda AlsaeediDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Mikhael BechelanyInstitut Européen des Membranes, IEM, UMR 5635, Univ Montpellier, ENSCM, CNRS, Montpellier, France.
Gemma K KinsellaSchool of Food Science and Environmental Health, Technological University Dublin, Dublin, Ireland.
Ahmed BarhoumSchool of Chemical and BioPharmaceutical Sciences, Technological University Dublin, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study reports the synthesis, structural characterization, and antibacterial evaluation of 5-(3-nitrophenyl)-1,3,4-thiadiazol-2-amine (NPTA), a commercially available thiadiazole derivative with potential antimicrobial activity. Methods: NPTA was synthesized through a green, one-pot condensation reaction between thiosemicarbazide and 3-nitrobenzoic acid in absolute ethanol, affording a pale-yellow crystalline solid with a melting point of 110 °C-112 °C. The compound was characterized using Fourier-transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopy, confirming its structure. Results: Discussion: These results demonstrate the promising antibacterial potential of NPTA and support its further development as a multifunctional thiadiazole-based antimicrobial candidate.

Indexed as

ADMET predictionantibacterial activityfrontier molecular orbitals (FMO)green synthesismolecular dockingmolecular dynamicsthiadiazole

Identifiers

PMID42487929
PMCPMC13388560

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.