SynthesisFrontiers in neurology
Prevalence of cognitive frailty in older adults with stroke in China: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Stroke is a leading cause of disability and mortality in older adults. Post-stroke cognitive frailty (CF) increases the risk of adverse outcomes. However, evidence regarding the prevalence of CF remains limited and inconsistent. This study aims to systematically evaluate the prevalence of CF among older adults with stroke in China and identifies factors associated with variation in prevalence, thereby informing future research directions and potential clinical considerations. Methods: We searched PubMed, Embase, Web of Science, Cochrane Library, China Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), VIP Database, and Wanfang Database for relevant studies reporting the prevalence of CF in Chinese older adults with stroke. The search covered the period from each database's inception to November 2024. Eligible studies were assessed for quality, and data were extracted. All analyses were performed using Stata 18.0 software. Results: Four Chinese studies involving 1,337 participants were included. Meta-analysis revealed a pooled prevalence of CF among older adults with stroke of 33% (95% CI: 28-39%). Subgroup analysis indicated a significantly higher prevalence of CF in stroke patients aged ≥80 years compared to those aged 60-79 years ( Conclusion: Available evidence suggests that the prevalence of CF among older adults with stroke in China appears to be substantial, with significant variations associated with alcohol consumption and advanced age. The particularly high prevalence estimates in patients with malnutrition or depression warrant increased clinical attention and further investigation into their relationship with post-stroke CF. Caution is warranted given the limited evidence base ( Systematic review registration: This systematic review was prospectively registered with PROSPERO (registration number: CRD42025643159).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.