ArticleAmerican journal of cardiovascular disease2026
Association between visceral adiposity index and hypertension in reproductive-aged women: evidence from NHANES 1999-2023.
Article in American journal of cardiovascular disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThe visceral adiposity index (VAI), an indicator of visceral fat accumulation and dysfunction, has been proposed as a potential marker for cardiometabolic risk. However, its association with hypertension in women of reproductive age remains unclear. Therefore, this study aims to investigate the association between VAI and the prevalence of hypertension in this specific population.
methodsThis cross-sectional study analyzed data from 2,571 women of reproductive age using the National Health and Nutrition Examination Survey (NHANES) database. Weighted multivariable logistic regression models were used to examine the relationship between VAI and hypertension, adjusting for potential confounders. Restricted cubic spline (RCS) modeling and two-piecewise linear regression were applied to evaluate the dose-response and threshold effects. Subgroup and interaction analyses were conducted across demographic and lifestyle factors.
resultsVAI was significantly and positively associated with the prevalence of hypertension in women of reproductive age (OR = 1.18, 95% CI: 1.08-1.29;
conclusionVAI is independently and nonlinearly associated with increased odds of hypertension in women of reproductive age, demonstrating a distinct threshold effect. These findings suggest that VAI may serve as a potential observational marker for evaluating cardiovascular risk in this population. Maintaining VAI below the 1.285 threshold could be considered in early cardiovascular prevention strategies.
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