Evidence map›Paper›PMID 42488564›Full record

ArticleFrontiers in pharmacology2026

Dosing of plant-derived extracellular vesicles in traditional Chinese medicine: current status, root causes, and standardization pathways.

Mingxin Guo

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mingxin GuoDepartment of Pharmacy, The Affiliated Yixing Hospital of Jiangsu University, Yixing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles derived from Traditional Chinese Medicine represent a growing research Frontier. However, no consensus exists regarding the definition, quantification, and reporting of administered doses. This methodological issue continues to compromise study reproducibility. This article draws on a comprehensive analysis of recent and foundational literature on TCM-derived extracellular vesicles. Analysis shows marked differences in measurement units, reporting formats, and magnitude ranges for both

Indexed as

dosageextracellular vesiclesnanomedicinestandardizationtraditional Chinese medicinevesicle yield

Identifiers

PMID42488564
PMCPMC13388247

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.