SynthesisFrontiers in physiology2026
The effects of lower limb blood flow restriction training on post-activation potentiation enhancement and fatigue: a meta-analysis.
Synthesis in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Objective: This study aims to systematically explore the effects of lower limb blood flow restriction (BFR) training on post-activation potentiation enhancement (PAPE) and the Rating of Perceived Exertion (RPE) through meta-analysis, and to identify optimal BFR protocol parameters, so as to provide scientific evidence for strength and conditioning training and rehabilitation interventions. Methods: A systematic search was conducted in PubMed, Web of Science, Scopus, and EBSCO databases to retrieve randomized controlled trials (RCTs) investigating the acute effects of lower limb BFR training on PAPE and RPE. The search timeframe covered the inception of each database to Dec 1, 2025. The Cochrane Collaboration's Risk of Bias Tool was used for literature quality assessment. Review Manager 5.4 and Stata 17.0 software were employed for statistical analysis, including heterogeneity testing, subgroup analysis, sensitivity analysis, and publication bias assessment. Results: A total of 15 eligible RCTs were included, involving 244 subjects aged 17-35 years. Meta-analysis results showed that lower limb BFR training significantly enhanced PAPE-related explosive performance [ Conclusion: Lower limb BFR training can effectively induce PAPE, with optimal effects achieved through multi-joint movements, rest intervals > 4 min, 40-60% AOP, and 40-70% 1RM intensity. Meanwhile, BFR training significantly elevates subjective fatigue (RPE), which is more prominent under conditions of knee flexion/compound exercises, shorter rest intervals, low intensity, and high occlusion pressure (> 60% AOP). Systematic Review Registration: https://inplasy.com/inplasy-2026-5-0041/, identifier INPLASY202430008.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.