ReviewInternational urogynecology journal2026
Long-Term Outcomes of Midurethral Slings: A Narrative Review of Objective and Patient-Reported Trajectories.
Review in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
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Abstract
introduction and hypothesisMidurethral sling (MUS) procedures are widely used for stress urinary incontinence (SUI), yet long-term outcomes remain incompletely characterized. This narrative review synthesizes evidence from studies with ≥10 years of follow-up, focusing on structural continence, patient-reported outcomes, late complications, and evolving storage symptoms.
methodsA PubMed-based narrative review was conducted for studies published between January 1996 and March 2026 reporting ≥10-year outcomes after MUS. Randomized trials and observational studies were included. Outcomes included subjective and objective continence, reoperation rates, mesh-related complications, de novo overactive bladder (OAB), and quality of life. Given heterogeneity in design and outcome definitions, findings were synthesized qualitatively through thematic grouping, temporal trajectory analysis, and cross-study interpretative comparison.
resultsSeventeen studies with 10-25+ years of follow-up were included. Objective cure rates exceeded 85-90% at 10 years and remained stable in retropubic cohorts. Subjective cure rates were more variable and declined in some cohorts despite preserved objective outcomes. Long-term randomized data suggested comparable continence between retropubic and transobturator slings, although some favored retropubic approaches under stricter definitions. De novo OAB increased over time, reaching 41.6% at 20 years, while transobturator mesh exposure rates increased from 2.5% at 13 years to 10% at 17 years. Patient-reported outcomes appeared increasingly influenced by storage symptoms, particularly de novo OAB, whereas the contribution of voiding dysfunction remained insufficiently characterized in the available literature.
conclusionsMUS procedures provide durable long-term structural continence. However, patient-perceived outcomes may evolve due to storage symptoms, particularly de novo OAB, and late complications. Although voiding dysfunction may contribute to long-term symptom burden, its role remains insufficiently characterized in the available literature. Longitudinal, domain-specific assessment beyond binary continence measures is needed.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.