Evidence map›Paper›PMID 42490013›Full record

ReviewApplied biochemistry and biotechnology2026

Recent Advances in Gold Nanoparticles as Antimicrobial Agents Against Pathogenic Bacteria: A Review (2022-2026).

Fahad Y Sabei, Awaji Y Safhi, Mohammed Sanad Alhussaini

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fahad Y SabeiDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia. Fsabei@jazanu.edu.sa.ORCID http://orcid.org/0000-0002-1412-5299
Awaji Y SafhiDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
Mohammed Sanad AlhussainiDepartment of Clinical Laboratory Science, College of Applied Medical Sciences, Shaqra University, Shaqra, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid emergence and global spread of antimicrobial resistance (AMR) have become a major public health challenge, making an urgent need for innovative antimicrobial strategies beyond conventional antibiotics. Among the various nanomaterials explored, gold nanoparticles (AuNPs) have attracted considerable attention because of their unique physicochemical properties, high surface-area-to-volume ratio, tunable surface chemistry, excellent biocompatibility, and ease of functionalization. These characteristics enable AuNPs to interact effectively with microbial cells and enhance the efficacy of antimicrobial agents. This review comprehensively summarizes recent advances (2022-2026) in the development and biomedical applications of AuNP-based antimicrobial agents against pathogenic bacteria. Unlike previous reviews that broadly discuss the biological or biomedical applications of AuNPs, the present review specifically focuses on their antimicrobial potential, recent progress, and current research trends. Particular emphasis is placed on the synthesis and surface modification of AuNPs, strategies for enhancing antibacterial activity, and the mechanisms underlying their antimicrobial effects, including membrane disruption, oxidative stress induction, biofilm inhibition, and interference with essential cellular processes. Furthermore, the review critically discusses the advantages and current limitations of AuNP-based antimicrobial systems, identifies existing research gaps, and outlines future directions for their translation into clinically relevant antimicrobial therapies. This review aims to provide a valuable and up-to-date resource for researchers developing next-generation nanomaterial-based antibacterial agents.

Indexed as

Antimicrobial activityAuNPsMembrane disruptionOxidative stress

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.