Evidence map›Paper›PMID 42490637›Full record

ArticlePLoS biology2026

Clonal drift in the aging gut: Mapping the fate of stem cells over time.

Tzu-Chiao Lu, Hongjie Li

Abstract readComment
In one paragraph

Article in PLoS biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Tzu-Chiao LuDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.ORCID https://orcid.org/0000-0001-9942-2307
Hongjie LiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.ORCID https://orcid.org/0000-0002-7332-7122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging tissues gradually lose cellular diversity due to stem cell exhaustion. A new PLOS Biology study utilizes advanced lineage tracing to track intestinal stem cell lineages across the life span. The findings reveal clonal attrition happens in early ages.

Indexed as

AgingIntestinesStem CellsAnimalsCell LineageClone CellsMice

Identifiers

PMID42490637
PMCPMC13395307

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.