ArticleAmerican journal of translational research2026
Shenzhu Guanxin formula alleviates atherosclerosis in rats via PI3K/Akt pathway inhibition: a comparative study of decoction and granule forms.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Shenzhu Guanxin Formula (SGF), a traditional Chinese medicinal compound comprising nine classical herbal constituents, has demonstrated clinical efficacy in the treatment of coronary heart disease. However, its bioactive components and mechanistic underpinnings in atherosclerosis (AS) remain elusive. This study aimed to elucidate the anti-atherosclerotic effects, bioactive constituents, therapeutic targets, and underlying mechanisms of both SGF decoction and granule formulations. An atherosclerotic rat model was established using a 16-week high-fat diet, supplemented with vitamin D
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