Evidence map›Paper›PMID 42491256›Full record

ArticleCureus2026

An Aggressive Presentation of Anti-melanoma Differentiation-Associated Gene 5 (MDA-5)-Positive Dermatomyositis With Rapidly Progressive Interstitial Lung Disease: A Case Report.

Zamanali Khakhar, Shreedhi M Patel, Rajiv Patel, Soraiya Manji, Fredrick Otieno, Sayed K Ali

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zamanali KhakharCollege of Medicine, University of Nairobi, Nairobi, KEN.
Shreedhi M PatelCollege of Medicine, University of Nairobi, Nairobi, KEN.
Rajiv PatelDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.
Soraiya ManjiDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.
Fredrick OtienoDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.
Sayed K AliDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-melanoma differentiation-associated gene 5 (MDA-5) dermatomyositis is an uncommon condition that is frequently complicated by rapidly progressive interstitial lung disease (RP-ILD), resulting in a poor prognosis. Due to its aggressive course, management is often challenging and requires timely interventions to improve outcomes. This case of a female patient with anti-MDA-5-positive DM and RP-ILD aims to document this unique and uncommon condition, its aggressive clinical course, associated complications, diagnostic challenges, and management considerations.

Indexed as

anti-mda-5 amyopathic dermatomyositisanti-mda-5 antibodiesdermatomyositisdermatomyositis-associated interstitial lung disease (dm-ild)rapidly progressive interstitial lung disease

Identifiers

PMID42491256
PMCPMC13376796

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.