ArticleGynecologic oncology reports2026
Pre-diagnosis symptoms reported among endometrial cancer survivors.
Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Objectives: Timely recognition of pre-diagnosis symptoms plays a key role in early diagnosis of endometrial cancer (EC). Symptom profiles may vary by conditions such as fibroids or obesity which are differentially distributed by race. We describe pre-diagnosis symptom reporting among EC survivors by race, fibroids history, and body mass index (BMI). Methods: We calculated prevalence ratios (PR) and 95% confidence intervals (CI) for 6 menstrual and 7 non-menstrual self-reported, pre-diagnosis symptoms using Poisson regression. We assessed participants' pre-diagnosis knowledge about postmenopausal bleeding and reporting of symptoms to healthcare providers. Results: Among 638 Carolina Endometrial Cancer Study participants, 36% self-identified as Black or African American and 64% as White. Women with fibroids (versus without) were more likely to report heavy periods (PR = 1.23, 95% CI 1.09-1.40), periods of >7 days (PR = 1.37, 95% CI 1.09-1.71), and non-menstrual symptoms (PR = 1.15, 95% CI 1.05-1.25). Women with a BMI >30 kg/m Conclusions: Pre-diagnosis symptom profiles varied by fibroids and obesity among endometrial cancer survivors. Low knowledge pertaining to postmenopausal bleeding as a potential symptom for endometrial cancer suggests opportunity for improved patient education.
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