Evidence map›Paper›PMID 42493801›Full record

ArticleMicrobiome2026

The Metaproteomics Initiative: five years of community-driven progress.

Tim Van Den Bossche, Lucia Grenga, Gelio Alves, Magnus Ø Arntzen, Dirk Benndorf, Madita Brauer, Daniel Figeys, Celine Henry, Robert L Hettich, Robert Heyer and 14 more

Abstract read
In one paragraph

Article in Microbiome, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Tim Van Den BosscheDepartment of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9052, Belgium.
Lucia GrengaDépartement Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SPI, Bagnols-sur-Cèze, France.
Gelio AlvesDivision of Intramural Research, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Magnus Ø ArntzenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Dirk BenndorfAnhalt University of Applied Sciences, Applied Biosciences and Process Engineering, Köthen, 06366, Germany.
Madita BrauerDepartment of Life Sciences and Medicine, Faculty of Science, Technology and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Daniel FigeysSchool of Pharmaceutical Sciences, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Celine HenryUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, 78350, France.
Robert L HettichBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
Robert HeyerMultidimensional Omics Data Analyses group, Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Bunsen-Kirchhoff-Straße 11, Dortmund, 44139, Germany.
Pratik D JagtapDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA.
Nico JehmlichDepartment of Molecular Toxicology, Helmholtz-Centre for Environmental Research - UFZ GmbH, Permoserstrasse 15, Leipzig, 04318, Germany.
Manuel KleinerDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA.
Leyuan LiState Key Laboratory of Medical Proteomics, National Center for Protein Sciences, Beijing, China.
Bart MesuereDepartment of Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium.
Martin PabstDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, Delft, 2629HZ, The Netherlands.
Jagroop PandhalSchool of Chemical, Materials and Biological Engineering, Faculty of Engineering, University of Sheffield, Sheffield, UK.
Phillip B PopeFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Jana SeifertInstitute of Animal Science, University of Hohenheim, Stuttgart, Germany.
Anke Trautwein-SchultDepartment of Microbial Proteomics, University of Greifswald, Institute of Microbiology, Greifswald, 17489, Germany.
Pieter VerschaffeltDepartment of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9052, Belgium.
Paul WilmesLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Jean ArmengaudDépartement Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SPI, Bagnols-sur-Cèze, France.
Benoit J KunathBioinformatics and Artificial Intelligence, Department of Medical Informatics, Luxembourg Institute of Health (LIH), Strassen, 1445, Luxembourg. benoit.kunath@lih.lu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Metaproteomics Initiative was officially launched in 2021 to strengthen collaboration, promote knowledge exchange, and support and lead standardization efforts within the growing metaproteomics community. Over the past 5 years, the Initiative has developed into a structured, global network of researchers. It has launched community-driven benchmark studies, helped shape emerging metadata and reporting standards, developed practical guidance and training materials, organized international symposia, and fostered connections across the microbiome research landscape ( https://metaproteomics.org/ ). We outline the Initiative's organization, activities, achievements, and ongoing efforts, and reflect on how sustained, community-led coordination has shaped the development of metaproteomics as a field. We further position the Grand Metaproteome Challenges as a next step toward coordinated, community-scale biological research, aimed at advancing functional microbiome studies across clinical, industrial, and environmental application domains, and invite engagement from the wider microbiome and omics communities. Video Abstract.

Indexed as

MicrobiotaProteomicsHumansMetagenomics

Identifiers

PMID42493801
PMCPMC13393725

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.