ArticlePsychiatry investigation2026
Mortality Rates According to the Time of Onset of Mental Disorders Among Patients With Coronavirus Disease 2019 in South Korea: A Nationwide Retrospective Study.
Article in Psychiatry investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study aimed to investigate the association between the timing of mental disorder diagnosis and all-cause mortality among patients with coronavirus disease 2019 (COVID-19) during the initial period of the pandemic.
methodsThis retrospective study used the K-COV-N cohort (Korea Disease Control and Prevention Agency-COVID-19-National Health Insurance Service cohort). Patients with confirmed COVID-19 between October 2020 and December 2021 were classified into three groups: those without mental disorders, those with pre-existing mental disorders, and those with newly diagnosed mental disorders during the COVID-19 pandemic. Logistic regression analysis was performed to estimate the association between mental disorder group and all-cause mortality.
resultsA total of 432,852 patients with COVID-19 were included in the analysis. Of these, 351,519 (81.21%) had no mental disorders, 54,846 (12.67%) had pre-existing mental disorders, and 26,487 (6.12%) had newly diagnosed mental disorders during the pandemic. The overall all-cause mortality rate was 0.72% (n=3,099). Compared with patients without mental disorders, those with pre-existing mental disorders (adjusted odds ratio [aOR], 1.33; 95% confidence interval [CI], 1.21-1.47) and those with newly diagnosed mental disorders (aOR, 1.63; 95% CI, 1.44-1.84) had higher odds of all-cause mortality.
conclusionAmong patients with COVID-19, both pre-existing and newly diagnosed mental disorders were associated with increased all-cause mortality, with a stronger association observed for newly diagnosed mental disorders.
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