Evidence map›Paper›PMID 42494098›Full record

ReviewThe British journal of radiology2026

Cardiovascular imaging with total-body PET.

Laura E Clark, Aidan Morgan, Craig Balmforth, Mark T MacMillan-John, Allison C Winarski, Phyo Khaing, David E Newby, Marc R Dweck

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura E ClarkBHF Centre for Research Excellence, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.ORCID 0000-0003-4765-0409
Aidan MorganBHF Centre for Research Excellence, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.
Craig BalmforthBHF Centre for Research Excellence, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.
Mark T MacMillan-JohnEdinburgh Imaging, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.ORCID 0000-0001-9102-1680
Allison C WinarskiBHF Centre for Research Excellence, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.
Phyo KhaingBHF Centre for Research Excellence, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.
David E NewbyBHF Centre for Research Excellence, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.ORCID 0000-0001-7971-4628
Marc R DweckBHF Centre for Research Excellence, University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.ORCID 0000-0001-9847-5917

Funding

British Heart Foundation CH/09/002/26360British Heart Foundation FS/CRTF/25/24719British Heart Foundation FS/SCRF/21/32010British Heart Foundation PG/24/12097British Heart Foundation RE/24/130012British Heart Foundation RG/F/22/110093DPFS MR/W029464/1Medical Research Council MR/Y009770/1MRC
6 · The paper itself

Abstract

Cardiovascular disease remains the leading cause of morbidity and mortality worldwide. PET enables non-invasive imaging of cardiovascular biology at the molecular level, providing insights into pathological processes that precede structural changes detectable by conventional imaging. While conventional PET has been used to investigate isolated cardiac pathologies, its short axial field-of-view (SAFOV) limits the exploration of multi-organ axes influencing cardiovascular disease. The advent of total-body PET systems represents a major advancement in molecular imaging, providing enhanced sensitivities with associated reductions in radiotracer dosing and acquisition times. Furthermore, long axial field-of-view (LAFOV) scanners enable simultaneous assessment of disease activity across the whole cardiovascular and multi-organ systems, facilitating the assessment of organ interactions and network analyses. The aim of this review is to explore the current uses of PET in the imaging of cardiovascular disease and to postulate how integration of total-body PET systems may enhance mechanistic understanding of these pathologies and provide new insights into their treatment.

Indexed as

Cardiovascular DiseasesPositron-Emission TomographyWhole Body ImagingHumansMolecular ImagingRadiopharmaceuticalsRadiopharmaceuticalsamyloidosisatherosclerosiscardiovascular diseaselong-axial field of viewmolecular imagingpositron emission tomographytotal-body PETvasculitis

Identifiers

PMID42494098
PMCPMC13489400

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.