Evidence map›Paper›PMID 42494182›Full record

ReviewJournal of food science2026

Engineering Strategies and Operations of Frozen Yogurt Formulated With GABA-Enriched Yogurt: A Review.

Wan Maizura Farhana Wan-Mazlan, Muhammad Ameer Ushidee-Radzi, Chong Shin-Yee, Yus Aniza Yusof, Wan Abd Al Qadr Imad Wan-Mohtar, Nur 'Aliaa Abd Rahman

Abstract readReview
In one paragraph

Review in Journal of food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wan Maizura Farhana Wan-MazlanDepartment of Process and Food Engineering, Faculty of Engineering, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Muhammad Ameer Ushidee-RadziFunctional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia.
Chong Shin-YeeFunctional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia.
Yus Aniza YusofLaboratory of Halal Science Research, Halal Products Research Institute, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Wan Abd Al Qadr Imad Wan-MohtarFunctional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-5384-4325
Nur 'Aliaa Abd RahmanDepartment of Process and Food Engineering, Faculty of Engineering, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.ORCID https://orcid.org/0000-0002-3942-2775

Funding

Universiti Malaya
6 · The paper itself

Abstract

Frozen yogurt formulated with γ-aminobutyric acid (GABA)-enriched yogurt represents a promising functional dairy matrix in response to growing interest in foods associated with cognitive health and neurological well-being. Although GABA has been associated with neurophysiological roles, product-specific clinical evidence for GABA-enriched frozen yogurt is not established. This review focuses on technological and engineering aspects rather than clinical efficacy. This review synthesizes recent advances in microbial biosynthesis and engineering strategies for producing high-quality GABA-frozen yogurt, including lactic acid bacteria strain selection (e.g., Levilactobacillus brevis, Lactiplantibacillus plantarum), fermentation optimization, and critical processing steps such as homogenization, aging, and dynamic freezing. Advanced technologies, including high-pressure processing, microfluidization, and the use of cryoprotectants, are discussed in relation to achieving target physicochemical properties. Target physicochemical properties for frozen yogurt systems typically include 35%-40% (w/w) total solids in the frozen yogurt mix and 20%-50% (v/v) overrun in the final frozen product, consistent with ranged reported for frozen yogurt and adjacent frozen dairy desserts; these values depend on formulation composition and processing conditions. Previous clinical trials and limited human studies suggest that GABA may contribute to anxiolytic and neuroprotective effects via the gut-brain axis; however, evidence specific to dairy-based delivery systems remains limited. Key challenges include maintaining GABA stability during frozen storage, scaling production, and navigating regulatory frameworks. Future perspectives highlight nanoencapsulation, synbiotic formulations, and computational modeling as tools to advance the development of GABA-enriched frozen yogurt as a functional dairy product supporting cognitive wellness.

Indexed as

gamma-Aminobutyric AcidYogurtFermentationFood HandlingFreezingHumansLactobacillalesgamma-Aminobutyric Acidfermentation engineeringfood processing technologyfrozen yogurtfunctional dairy productsGABA‐enriched dairy products

Identifiers

PMID42494182
PMCPMC13396824

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.