Evidence map›Paper›PMID 42494574›Full record

ArticleExploration (Beijing, China)2026

Artificial Chlorella Biohybrids for Alleviation of Cartilage Degeneration in Osteoarthritis.

Yongyun Chang, Keyu Kong, Minghao Jin, Shasha Liu, Yangzi Yang, Yingchun Zhu, Hua Qiao, Wenxuan Fan, Xinru Wu, Jingwei Zhang and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Exploration (Beijing, China), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yongyun ChangShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Keyu KongShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Minghao JinShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Shasha LiuShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Yangzi YangDepartment of Orthopedic Surgery Spine Center Changzheng Hospital Navy Medical University Shanghai China.
Yingchun ZhuKey Laboratory of Inorganic Coating Materials Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai P. R. China.
Hua QiaoShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Wenxuan FanShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Xinru WuShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Jingwei ZhangShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Yansong QiDepartment of Orthopedics Inner Mongolia People's Hospital Hohhot China.
Yongsheng XuDepartment of Orthopedics Inner Mongolia People's Hospital Hohhot China.
Xiang FengDepartment of Orthopedics People's Hospital of Shigatse City Xizang Autonomous Region Shigatse City China.
Pingcuo NimaDepartment of Orthopedics People's Hospital of Shigatse City Xizang Autonomous Region Shigatse City China.
Piting JiDepartment of Orthopedics People's Hospital of Shigatse City Xizang Autonomous Region Shigatse City China.
Tariel MamuladzeNovosibirsk Scientific Research Institute of Traumatology and Orthopedics. Ya.L. Tsivyan: Novosibirsk Novosibirsk Oblast Russia.
Andrei A KorytkinNovosibirsk Scientific Research Institute of Traumatology and Orthopedics. Ya.L. Tsivyan: Novosibirsk Novosibirsk Oblast Russia.
Huiwu LiShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Jingke FuShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.ORCID https://orcid.org/0000-0003-0554-9046
Zanjing ZhaiShanghai Key Laboratory of Orthopedic Implants Department of Orthopedics Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA), one of the most common chronic joint diseases, is characterised by cartilage imbalance and disruption of the cartilage extracellular matrix. In this study, we observed impaired mitophagy and glucose metabolism disorders in OA chondrocytes, which exacerbated cartilage degeneration. And we unveil

Indexed as

cartilage degenerationchondrocytesglycolysismitophagyosteoarthritis

Identifiers

PMID42494574
PMCPMC13394597

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.