ArticleFrontiers in oncology2026
Eight-year disease-free survival in clear cell adenocarcinoma of the urethra with surgery alone: a case report and literature review.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We report a 39-year-old woman with clear cell adenocarcinoma of the urethra (CCAU). She was treated with surgery alone and has survived 8 years without recurrence. The patient had painless hematuria. Imaging showed a 5.1 cm urethral mass. The tumor invaded the bladder and vagina (clinical stage T3N2M0). Urine cytology confirmed the diagnosis, which is unusual for CCAU. She underwent laparoscopic radical cystectomy, lymph node dissection, and cutaneous ureterostomy. Pathology showed clear cell adenocarcinoma with CK7+/PAX8+. The final pathological stage was T3N0M0. She did not receive adjuvant therapy. Follow-up through January 2025 (8 years) showed no tumor recurrence, which appears to be rare among reported cases.
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