Evidence map›Paper›PMID 42494653›Full record

ArticleJournal of bone oncology2026

Integrative machine learning and multi-omics identify a centromere gene signature and validate B3GALT4 as a tumor suppressor in osteosarcoma.

Wenchao Yao, LinPing Zhang, Zhen Jiang, Tao Bao, Junhua Ma, Jiangbo Nie

Abstract read
In one paragraph

Article in Journal of bone oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenchao YaoDepartment of Orthopedics, Chun'an Country First People's Hospital, Zhejiang Province People's Hospital Chun'an Branch, Hangzhou, Zhejiang, China.
LinPing ZhangDepartment of Orthopedics, Chun'an Country First People's Hospital, Zhejiang Province People's Hospital Chun'an Branch, Hangzhou, Zhejiang, China.
Zhen JiangDepartment of Orthopedics, Chun'an Country First People's Hospital, Zhejiang Province People's Hospital Chun'an Branch, Hangzhou, Zhejiang, China.
Tao BaoDepartment of Orthopedics, Chun'an Country First People's Hospital, Zhejiang Province People's Hospital Chun'an Branch, Hangzhou, Zhejiang, China.
Junhua MaDepartment of Orthopedics, Chun'an Country First People's Hospital, Zhejiang Province People's Hospital Chun'an Branch, Hangzhou, Zhejiang, China.
Jiangbo NieDepartment of Orthopedics, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Centromere-associated genes are linked to genomic instability and tumor progression, yet their significance and immunological roles in osteosarcoma (OS) remain undefined.

Indexed as

B3GALT4CPGMMulti-omicsOsteosarcoma

Identifiers

PMID42494653
PMCPMC13393646

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.