Evidence map›Paper›PMID 42495250›Full record

ArticleFrontiers in pediatrics2026

Neonatal Noonan syndrome with acute kidney injury and systemic capillary leak syndrome caused by a

Chunfang Gao, Fanli Kong, Xuwei Tao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chunfang Gao *Division of Neonatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Fanli Kong *Pain and Sleep Treatment Center, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Xuwei TaoDivision of Neonatology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To report a rare case of neonatal Noonan syndrome (NS) caused by a Methods: The clinical data of a neonate with NS admitted to the Neonatal Intensive Care Unit of Wuhan Children's Hospital were retrospectively analyzed, and Results: The proband was a term female neonate presenting with progressive acute kidney injury (AKI), systemic capillary leak syndrome (SCLS), refractory chylothorax, and a large patent ductus arteriosus. Whole-exome sequencing identified a Conclusion: The

Indexed as

acute kidney injuryNoonan syndromeRAS-MAPK pathwayRIT1 genesystemic capillary leak syndrome

Identifiers

PMID42495250
PMCPMC13391526

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.