Evidence mapPaperPMID 42495347Full record

ArticleACS omega2026

Sulfonylated Goniothalamin and Piplartine Derivatives Exhibit Selective Antiproliferative Activity on Breast Cancer Cells via Oxidative Stress-Mediated Mechanisms.

Julia Louise Moreira Nacif, Aloisio de Andrade Bartolomeu, Simone da Silva Lamartine-Hanemann, Bruno Zavan, Luiza de Mello Nascimento, Ester Siqueira Caixeta, Alexandre Ferro Aissa, Ronaldo Aloise Pilli, Marisa Ionta

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia Louise Moreira NacifLaboratório de Avaliação de Protótipos Antitumorais (LAPAN), Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais zip code 37-130-001, Brazil.
Aloisio de Andrade BartolomeuInstituto de Química, Universidade Estadual de Campinas (UNICAMP), Campinas, SP zip code 13083-970, Brazil.
Simone da Silva Lamartine-HanemannLaboratório de Avaliação de Protótipos Antitumorais (LAPAN), Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais zip code 37-130-001, Brazil.
Bruno ZavanLaboratório de Avaliação de Protótipos Antitumorais (LAPAN), Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais zip code 37-130-001, Brazil.
Luiza de Mello NascimentoLaboratório de Avaliação de Protótipos Antitumorais (LAPAN), Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais zip code 37-130-001, Brazil.
Ester Siqueira CaixetaLaboratório de Avaliação de Protótipos Antitumorais (LAPAN), Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais zip code 37-130-001, Brazil.
Alexandre Ferro AissaLaboratório de Avaliação de Protótipos Antitumorais (LAPAN), Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais zip code 37-130-001, Brazil.ORCID https://orcid.org/0000-0002-0759-4011
Ronaldo Aloise PilliInstituto de Química, Universidade Estadual de Campinas (UNICAMP), Campinas, SP zip code 13083-970, Brazil.ORCID https://orcid.org/0000-0002-5919-7763
Marisa IontaLaboratório de Avaliação de Protótipos Antitumorais (LAPAN), Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais zip code 37-130-001, Brazil.ORCID https://orcid.org/0000-0001-8796-1426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is a highly heterogeneous and treatment-resistant malignancy, underscoring the urgent need for novel therapeutic strategies. In this study, we investigated the antitumor potential of sulfonylated derivatives of goniothalamin (compound

Identifiers

PMID42495347
PMCPMC13393042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.