Evidence mapPaperPMID 42495705Full record

ReviewFrontiers in physiology2026

Caffeine and human performance: from molecular mechanisms to exercise and recovery.

Jingzhi Leng, Jingjing Yu, Zheheng Li, Yimin Zhang, Juntao Cui

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jingzhi Leng *College of Sports and Human Science, Key Laboratory of Sports and Physical Fitness Health of Ministry of Education, Beijing Sport University, Beijing, China.
Jingjing Yu *College of Sports and Human Science, Key Laboratory of Sports and Physical Fitness Health of Ministry of Education, Beijing Sport University, Beijing, China.
Zheheng LiDepartment of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Yimin ZhangCollege of Sports and Human Science, Key Laboratory of Sports and Physical Fitness Health of Ministry of Education, Beijing Sport University, Beijing, China.
Juntao CuiSchool of Physical Education, Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caffeine, the world's most widely consumed psychoactive substance, is a well-established ergogenic aid. Its performance-enhancing effects are mediated through multiple, interacting mechanisms that follow a dose-dependent hierarchy. The primary and most significant action at common dietary doses is the antagonism of central adenosine A

Indexed as

adenosine receptor antagonistcaffeineenergy metabolismexercise performancesport nutrition

Identifiers

PMID42495705
PMCPMC13391340

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.