Evidence mapPaperPMID 42496322Full record

ReviewNeuroSci2026

Structural and Functional Brain Alterations Induced by Noise Exposure: A Comprehensive Review.

Hanna Valeria Venegas-Mora, Octavio Ispanixtlahuatl-Meraz, Diana Emilia Martínez-Fernández, Irene Guadalupe Aguilar-García, David Fernández-Quezada

Abstract readReview
In one paragraph

Review in NeuroSci, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hanna Valeria Venegas-MoraInstituto de Neurociencias Traslacionales, Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada 950, Guadalajara 44340, Mexico.
Octavio Ispanixtlahuatl-MerazLaboratorio de Carcinogénesis y Toxicología, Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Los Reyes Iztacala, Tlalnepantla de Baz, Estado de México 54090, Mexico.ORCID 0000-0002-7029-6826
Diana Emilia Martínez-FernándezInstituto Transdisciplinar de Investigación y Servicios (ITRANS), Universidad de Guadalajara (UdeG), Zapopan 45150, Mexico.ORCID 0000-0002-3640-4870
Irene Guadalupe Aguilar-GarcíaInstituto de Neurociencias Traslacionales, Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada 950, Guadalajara 44340, Mexico.
David Fernández-QuezadaInstituto de Neurociencias Traslacionales, Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada 950, Guadalajara 44340, Mexico.ORCID 0000-0002-6943-7492

Funding

Apoyo para Pago de Publicación de Artículos Científicos APPAC-VIII-CUCS 2026Programa de Apoyo a la Mejora en las Condiciones de Producción de las Personas Integrantes del SNII y SNCA(PROSNII) 2025 U006EST
6 · The paper itself

Abstract

Noise exposure has become an increasingly prevalent public health concern, with effects extending beyond the auditory system. Accumulating evidence indicates that chronic noise exposure induces both structural and functional alterations in the central nervous system, ultimately affecting cognitive and emotional processes. This review summarizes the impact of noise on key brain regions, including the hippocampus, prefrontal cortex, and auditory cortex. Structurally, noise exposure is associated with reduced neurogenesis, dendritic remodeling, synaptic loss, alterations in white matter and changes in glial activity. Functionally, it disrupts synaptic plasticity mechanisms-such as long-term potentiation and long-term depression-as well as neuronal connectivity, leading to impairments in higher-order cognitive and behavioral functions. These effects are mediated by interconnected mechanisms, including activation of the hypothalamic-pituitary-adrenal axis, neuroinflammation, oxidative stress, and alterations in neurotrophic signaling.

Indexed as

behaviorbraincognitionneuroplasticitynoise exposure

Identifiers

PMID42496322
PMCPMC13398173

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.