Evidence mapPaperPMID 42496753Full record

ReviewCurrent cardiology reports2026

Impact of Hypertensive Disorders of Pregnancy on Maternal and Offspring Cardiovascular Health.

Falastine Das, Susmita Parashar, Aparna Kulkarni

Abstract readReview
In one paragraph

Review in Current cardiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Falastine DasCohen Children's Heart Center, Northwell Health, Cohen Children's Medical Center, New Hyde Park, NY, USA.
Susmita ParasharDivision of Cardiology, Emory School of Medicine, Atlanta, GA, USA.
Aparna KulkarniCohen Children's Heart Center, Northwell Health, Cohen Children's Medical Center, New Hyde Park, NY, USA. aparnapat@yahoo.com.ORCID https://orcid.org/0000-0003-2540-6931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertensive disorders of pregnancy (HDP) affect 5-10% of pregnancies globally and are a leading cause of maternal and fetal morbidity and mortality. Beyond their acute obstetrics impact, HDP unmask a lifelong cardiovascular (CV) vulnerability in affected women and confer intergenerational risk to their offspring. PURPOSE OF REVIEW: In this review, we discuss the latest evidence regarding the CV risk profiles following HDP in the mothers and their offspring. RECENT

findingsIn mothers, HDP is associated with a 7.29-fold increased risk of new chronic hypertension (HTN) within 24 months postpartum and long-term risks of heart failure, coronary heart disease and stroke. Offspring exposed carry a 1.5-fold increased risk for adult HTN and increased risks for ischemic heart disease and stroke. We review evidence on potential pathophysiologic mechanisms including shared genetic, epigenetic programming and persistent immune dysregulation that contribute to the CV risk. We make recommendations on surveillance strategies in mothers and their offspring beginning in the immediate postpartum period and for lifelong follow-up. Management strategies of the CV risk factors, using latest guidelines are discussed. We suggest future directions for research and intervention. Integrated maternal-offspring CV care, women-specific risk prediction tools and equity focused research are needed to reduce the intergenerational burden of HDP.

Indexed as

Cardiovascular DiseasesHypertension, Pregnancy-InducedPrenatal Exposure Delayed EffectsDevelopmental Origins of Health and DiseaseFemaleHeart Disease Risk FactorsHumansHypertensionPregnancyRisk FactorsStrokeHypertensive disorders of pregnancyIntergenerational transmission of diseaseMaternal cardiovascular healthOffspring cardiovascular health

Identifiers

PMID42496753
PMCPMC13400458

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.