ArticleAnnals of Ibadan postgraduate medicine2026
PREVALENCE, CHARACTERISTICS AND TREATMENT OUTCOMES OF HPV POSITIVE OROPHARYNGEAL CARCINOMA IN AFRICA: A SYSTEMATIC REVIEW AND META-ANALYaSIS.
Article in Annals of Ibadan postgraduate medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
9 authors.
Funding
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Abstract
Background: Human papillomavirus (HPV) is a sexually transmitted virus implicated in several anogenital and oropharyngeal malignancies. Rising oral sexual practices have been suggested as one factor influencing oral HPV transmission and associated malignancies in some populations. This review aimed to estimate the pooled prevalence, summarize characteristics, and synthesize treatment and outcome data for HPV-positive oropharyngeal carcinoma (OPC) in Africa. Methods: An initial PROSPERO registration was done (CRD420251012776), and the systematic review followed the PRISMA guidelines. The study included original English peer-reviewed research works that reported data on the prevalence, characteristics, and treatment outcomes of HPV-positive oropharyngeal cancers. The risk of bias was assessed for all the studies using Cochrane's ROBIN-E tool. Systematic synthesis and meta-analysis were used to synthesise extracted data. Results: 15 studies involving a total of 896 participants met the inclusion criteria and were included in the meta-analysis. The pooled prevalence of HPV-associated oropharyngeal cancer across the 15 African-based studies was 12% (95% CI: 8%-19%), with significant heterogeneity (I Conclusion: There were limited data of treatment and outcomes underscoring the need for improved reporting standards and longitudinal data across African settings.
Indexed as
Identifiers
42499469PMC13399177What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.