ArticleFrontiers in surgery2026
Trimodal prehabilitation and psychological outcomes in colorectal cancer surgery: preliminary findings from a single-center randomized trial.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06443203 (A Randomized Controlled Clinical Trial on Multimodal Prehabilitation in Colorectal Cancer Patients to Improve Functional Capacity and Lower Postoperative Complications.), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Clinical Trial on Multimodal Prehabilitation in Colorectal Cancer Patients to Improve Functional Capacity and Lower Postoperative Complications.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Surgery for colorectal cancer (CRC) entails significant physical and psychological stress. This clinical trial evaluated whether a trimodal prehabilitation program combining exercise, nutritional support, and psychological counseling could reduce anxiety and depression while improving health-related quality of life (HRQoL) within an Enhanced Recovery After Surgery (ERAS) pathway. Methods: In this single-blind randomized controlled trial, an interim analysis was conducted on 45 patients undergoing elective CRC surgery, assigned to trimodal prehabilitation ( Results: GAD-7 scores decreased from 6.2 ± 5.1 to 2.2 ± 3.1 in the intervention group and from 4.7 ± 4.8 to 2.9 ± 2.8 in controls (between-group Conclusions: Trimodal prehabilitation within an ERAS pathway reduces anxiety and improves perceived health status in patients undergoing CRC surgery. Larger multicenter studies are warranted to confirm its effects on depression and long-term outcomes. Clinical trial registration: https://clinicaltrials.gov/study/NCT06443203, identifier NCT06443203.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.