Evidence map›Paper›PMID 42499681›Full record

ArticleActa naturae

Reconstruction and Paleogenetic Characterization of the Genome of Princess Maria Vsevolozha, Wife of Grand Prince Vsevolod the Big Nest.

K V Zhur, M V Leonova, F S Sharko, E D Pankratova, A V Sirenov, D S Korobov, M V Dobrovolskaya, N A Makarov, E B Prokhortchouk

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Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

K V ZhurFederal Research Center "Fundamentals of Biotechnology", Russian Academy of Sciences, Moscow, 119071 Russia.
M V LeonovaFederal Research Center "Fundamentals of Biotechnology", Russian Academy of Sciences, Moscow, 119071 Russia.
F S SharkoNational Research Center "Kurchatov Institute", Moscow, 123182 Russia.
E D PankratovaFederal Research Center "Fundamentals of Biotechnology", Russian Academy of Sciences, Moscow, 119071 Russia.
A V SirenovSaint Petersburg Institute of History, Russian Academy of Sciences, St. Petersburg, 197110 Russia.
D S KorobovInstitute of Archeology, Russian Academy of Sciences, Moscow, 117292 Russia.
M V DobrovolskayaInstitute of Archeology, Russian Academy of Sciences, Moscow, 117292 Russia.
N A MakarovInstitute of Archeology, Russian Academy of Sciences, Moscow, 117292 Russia.
E B ProkhortchoukFederal Research Center "Fundamentals of Biotechnology", Russian Academy of Sciences, Moscow, 119071 Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grand Prince of Vladimir Vsevolod the Big Nest and his wife Maria Vsevolozha (Shvarnovna) had twelve children, eight of whom were sons; Grand Prince Alexander Yaroslavich Nevsky was their grandson. Two competing hypotheses exist regarding the origin of Maria Vsevolozha, attributing it to either Ossetian or Czech nobility. Maria Shvarnovna was buried in the Knyaginin Monastery in Vladimir, Russia. Although her remains were reinterred several times, they were never moved from the original burial location. During the 2015 restoration works, skeletal remains, presumably belonging to Maria Shvarnovna, were sampled for paleogenetic analysis in order to determine their origin. More than 144,000 single nucleotide polymorphisms (SNPs) were identified. Their analysis demonstrated that the remains belong to a female carrying mitochondrial haplogroup U4b1a4 and unambiguously confirmed a third-degree biological relationship (great-grandmother-great-grandson) with Prince Dmitry Alexandrovich, the son of Grand Prince Alexander Yaroslavich Nevsky. This result fully corresponds to the genealogical relationships described in medieval chronicles. A multivariate statistical analysis of the genome revealed the two most probable proximal genetic sources of her origin: an Alan component, understood here in a broad cultural-historical sense encompassing populations of the Early and High Middle Ages, and an East Eurasian component. Among medieval populations, the genome of Maria Shvarnovna shows the closest genetic affinity to individuals associated with the SaltovoMayaki archaeological culture, characteristic of the Don forest-steppe region and resulting from the migration of Alan tribes, as well as to individuals from the Kara-Zhygach necropolis (14

Indexed as

Alan originancient DNAIBD analysisPrincess Maria ShvarnovnaRurikidswhole-genome sequencing

Identifiers

PMID42499681
PMCPMC13399679

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.