ArticleIntegrative medicine research2026
Comparative effectiveness of Chinese herbal medicine versus liraglutide for weight loss in adults with obesity: A 12-month real-world target trial emulation study.
Article in Integrative medicine research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Chinese herbal medicine (CHM) is commonly used for weight control in Taiwan. This study aimed to compare the effectiveness and mechanisms of a fixed combination of CHM with liraglutide using a target trial emulation real-world study. Methods: From January 1, 2013, to December 31, 2018, subjects from the multi-institutional Chang Gung Research Database (CGRD) with a BMI ≥ 25 kg/m² received a fixed combination of Ma-Xing-Gan-Shi-Tang and Results: Among 376 subjects, 135 (35.9%) used MCLOW, who lost more weight from baseline (-6.07 [95% CI:6.90 to -5.24] vs. -1.66 [95% CI:2.22 to -1.1] kg; p-value < 0.001), and had a higher proportion achieved weight reductions of ≥ 5% and ≥ 10% (68.15% vs. 23.65%, Conclusion: The CHM formula MCLOW appears to have promising effects on weight loss, with mechanisms differing from but complementary to those of Western medicines.
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