Evidence map›Paper›PMID 42502129›Full record

ReviewEye (London, England)2026

Photoreceptor replacement: a disease-agnostic approach for the treatment of advanced retinal degeneration.

Rachael A Pearson

Abstract readReview
In one paragraph

Review in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Rachael A PearsonOcular Cell and Gene Therapy Group, Centre for Gene Therapy and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom. rachael.pearson@kcl.ac.uk.ORCID http://orcid.org/0000-0002-1107-1969

Funding

RCUK | Medical Research Council (MRC) MR/T002735/2RCUK | Medical Research Council (MRC) MR/V038559/1RCUK | Medical Research Council (MRC) UKRI3826
6 · The paper itself

Abstract

Retinal dystrophies such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD) affect millions of individuals worldwide and remain leading causes of irreversible blindness. Photoreceptor transplantation has emerged as a promising and disease-agnostic therapeutic approach for restoring vision in advanced degenerative retinal diseases characterised by the loss of rods and/or cones. This brief review summarises some key areas of progress and future directions for photoreceptor replacement therapy, with consideration given to translating pre-clinical findings to the clinic.

Indexed as

Photoreceptor Cells, VertebrateRetinal DegenerationAnimalsHumans

Identifiers

PMID42502129
PMCPMC13601496

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.