Evidence map›Paper›PMID 42502255›Full record

ArticleJournal of the International AIDS Society2026

Latin America and the Caribbean: Challenges and Opportunities for HIV Treatment and Prevention.

Mateo Prochazka, Kelika A Konda, Omar Sued, Hortencia Peralta, Andrea Boccardi, Thiago S Torres, Monica Alonso, Valdilea Veloso, Beatriz Grinsztejn

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mateo ProchazkaWorld Health Organization, Geneva, Switzerland.
Kelika A KondaKeck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-2836-0174
Omar SuedPan American Health Organization, Washington, DC, USA.ORCID https://orcid.org/0000-0001-5818-770X
Hortencia PeraltaPan American Health Organization, Washington, DC, USA.
Andrea BoccardiUNAIDS, Brasilia, Brazil.
Thiago S TorresFundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil.
Monica AlonsoPan American Health Organization, Washington, DC, USA.
Valdilea VelosoFundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil.
Beatriz GrinsztejnFundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn Latin America, there are rising numbers of new HIV acquisitions, while the Caribbean has achieved decreases in both new acquisitions and AIDS-related deaths. The Latin American and Caribbean (LAC) region has worked towards widely available treatment for people with HIV (PWHIV) within public health systems and, in Latin America, has relied principally on domestic financing to do so. DISCUSSION: While new methods of prevention are in the process of being incorporated into regional HIV programmes, the HIV cascade of care remains below the UNAIDS goals. Only 17 of the 32 LAC countries (53%) report on the three pillars. Only Chile achieved >95% in two of the three pillars, with 95% of PWHIV knowing their status and 95% of people on treatment having a suppressed viral load. However, only 75% of those who know their status were on treatment. In the Caribbean, very little data is available, with all three cascade pillars missing for six of the countries. Only the Bahamas reached the 95% threshold for any of the cascade steps. Additionally, in the Caribbean, the viral suppression step of the cascade is much lower on average than in Latin America, with no countries reaching 80%. Biomedical HIV prevention with pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) is still being adopted and scaled up among populations in need. Scale-up of prevention efforts remains hindered by structural limitations of the health system, legal and policy limitations such as continuing to require informed consent for HIV testing and policies that block task-shifting, as well as persistent stigma. Recent reductions in international funding for HIV may adversely influence HIV programmes in LAC, which have relied on these for initial scale-up of innovations.

conclusionsAccelerating differentiated and simplified delivery of PrEP and PEP, alongside sustained progress towards universal treatment coverage and viral suppression, are all essential for translating existing scientific advances into measurable progress towards HIV elimination in the region.

Indexed as

Anti-HIV AgentsHIV InfectionsCaribbean RegionHumansLatin AmericaAnti-HIV AgentsCaribbeanHIV careHIV cascadeHIV preventionLatin AmericaPrEP

Identifiers

PMID42502255
PMCPMC13401677

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.