ArticleFood science & nutrition2026
Effect of Chitooligosaccharides-Combination Fortified Noodles Intervention on Visceral Adiposity and Serum Metabolites in a High-Risk Occupational Cohort of Young Seafarers.
Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Offshore seafarers face a unique "metabolically obesogenic" environment, predisposing them to an elevated risk of central obesity and metabolic disorders, even at a young age, creating a critical need for feasible, on-board nutritional interventions. This study aimed to evaluate the effects of Chitooligosaccharides-combination fortified noodles on body composition in young male seafarers and to elucidate the underlying systemic metabolic mechanisms. A self-controlled trial was conducted with 73 participants, who underwent a 4-week placebo phase followed, after a washout, by a 4-week intervention phase consuming functional noodles every other day. Clinical assessments included body weight, waist circumference, body composition indices, and serum lipid profiles, and untargeted metabolomics was performed on a subset of 38 participants. Compared with the placebo phase, oligosaccharide intervention significantly reduced waist circumference (WC), visceral fat area (VFA), serum leptin and LDL-cholesterol (LDL-C) levels, and increased skeletal muscle mass index, with no significant change in body weight. Linear mixed models confirmed significant net reductions in VFA (
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