ReviewCells2026
Molecular Basis of Glia-ECM Interplay in Central Nervous System Homeostasis and Plasticity.
Review in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Interactions between glial cells and the central nervous system (CNS) extracellular matrix (ECM) maintain neural homeostasis and plasticity. In contrast to traditional reviews focusing on biochemistry, this work summarizes the structural and mechanical properties of major ECM subtypes, and illustrates how mechanical and biochemical signals jointly regulate glial activity via key mechanosensitive pathways. Glia in turn dynamically remodel ECM, forming a reciprocal regulatory network. This paper also analyzes characteristic mechanical disorders in Alzheimer's disease, multiple sclerosis and traumatic brain injury, and addresses targeted therapeutic strategies. Current research challenges and emerging interdisciplinary directions are also discussed. This review provides a valuable reference for exploring neurological disease mechanisms and developing new therapies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.