Expression of Rate-Limiting Enzymes of Melatonin Synthesis in Several Extrapineal Organs During Pregnancy in Ewes.

Yanshu Xu, Haozhe Hou, Yang Yang, Dongsheng Gao, Leying Zhang, Ling Yang

Abstract read

In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanshu XuSchool of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China.

Haozhe HouSchool of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China.

Yang YangSchool of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China.

Dongsheng GaoSchool of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China.

Leying ZhangSchool of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China.ORCID 0000-0002-8612-8325

Ling YangSchool of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China.ORCID 0000-0003-4385-0024

Funding

Hebei Provincial Department of Science and Technology C2024402023

6 · The paper itself

Abstract

Melatonin is not only produced by the pineal gland but is also synthesized in extrapineal organs. It plays a key role in antioxidant defense and immune regulation during pregnancy. Two key rate-limiting enzymes are involved in the melatonin synthesis, aralkylamine N-acetyltransferase (AANAT), and acetylserotonin O-methyltransferase (ASMT). Nevertheless, it remained unclear whether pregnancy affects the expression of AANAT and ASMT in extrapineal organs. In this study, ovine maternal thymus, spleen, liver, lymph nodes, thyroid, duodenum, and endometrium were collected on day 16 of the estrous cycle (N16), and on days 13, 16, 25, and 70 (G70) of gestation (

Indexed as

Acetylserotonin O-MethyltransferaseArylalkylamine N-AcetyltransferaseMelatoninAnimalsEndometriumFemaleLiverLymph NodesPregnancySheepSpleenThymus GlandThyroid GlandAcetylserotonin O-MethyltransferaseArylalkylamine N-AcetyltransferaseMelatoninacetylserotonin O-methyltransferasearalkylamine N-acetyltransferaseextrapineal organspregnancysmall-tail Han ewes

Identifiers

PMID42509839

DOI10.3390/biom16071047

PMCPMC13406823

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.