Evidence map›Paper›PMID 42510496›Full record

ReviewBioengineering (Basel, Switzerland)2026

Electron-Mediated Contrast Mechanisms in Biomedical Imaging: A Narrative Review and the Implication for Emerging Techniques.

Samantha Condo, Reisin Cai, Kejia Cai

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samantha CondoDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0001-6914-8829
Reisin CaiBlue Valley Northwest High School, Overland Park, KS 66213, USA.
Kejia CaiDepartment of Radiology and Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0003-1511-4273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electron behaviors-including how electrons interact with energy, matter, and magnetic fields-form the foundation of many biomedical imaging modalities, including X-ray imaging, computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), optical imaging, electron microscopy, atomic force microscopy, and electron paramagnetic resonance (EPR). These interactions allow visualization of internal structures, molecular processes, tissue composition, oxygenation, redox biology, and high-resolution cellular or surface features. This narrative review provides an overview of key electron-associated mechanisms and their applications in biomedical imaging. Advanced MRI methods, including magnetic resonance spectroscopy, chemical exchange saturation transfer, relayed nuclear Overhauser effect imaging, dynamic nuclear polarization, and hyperpolarized 13C MRI, are highlighted as examples of molecular and metabolic imaging. By comparing modalities across contrast mechanism, spatial and temporal scale, penetration depth, sensitivity, clinical utility, and technological maturity, this review provides a framework for understanding established imaging approaches and contextualizing emerging biomedical imaging technologies.

Indexed as

biomedical imagingchemical exchange saturation transfer (CEST)electron paramagnetic resonance (EPR)electron physicsimaging contrast mechanismsmagnetic resonance imaging (MRI)molecular imagingnarrative review

Identifiers

PMID42510496
PMCPMC13403628

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.