Evidence map›Paper›PMID 42510537›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Effect of Ubiquinol on Cognitive Function, Blood Pressure, Arterial Stiffness, and Biomarkers of Oxidative Stress and Inflammation in the Elderly: A Randomized Trial.

Madeleine C Nankivell, Franklin Rosenfeldt, Jeffery M Reddan, Judy B de Haan, Cherry Zhang Ping, Beaudan Campbell-Brown, Andrew Pipingas, Matthew P Pase, Ruchong Ou, Matthew B Cooke and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Madeleine C NankivellCentre for Mental Health and Brain Sciences, Swinburne University, Melbourne 3122, Australia.ORCID 0009-0007-9322-1644
Franklin RosenfeldtCentre for Mental Health and Brain Sciences, Swinburne University, Melbourne 3122, Australia.ORCID 0009-0007-8188-984X
Jeffery M ReddanCentre for Mental Health and Brain Sciences, Swinburne University, Melbourne 3122, Australia.
Judy B de HaanCardiovascular Inflammation and Redox Biology Lab, Baker Heart & Diabetes Institute, Melbourne 3004, Australia.
Cherry Zhang PingCardiovascular Inflammation and Redox Biology Lab, Baker Heart & Diabetes Institute, Melbourne 3004, Australia.
Beaudan Campbell-BrownSchool of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Melbourne 3168, Australia.
Andrew PipingasCentre for Mental Health and Brain Sciences, Swinburne University, Melbourne 3122, Australia.
Matthew P PaseSchool of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Melbourne 3168, Australia.ORCID 0000-0002-4143-8485
Ruchong OuCardiovascular Inflammation and Redox Biology Lab, Baker Heart & Diabetes Institute, Melbourne 3004, Australia.
Matthew B CookeSport, Performance and Nutrition Research Group, School of Allied Health, Human Services and Sport, La Trobe University, Bundoora 3086, Australia.
David L HareDepartment of Cardiology, Austin Health, Melbourne 3084, Australia.ORCID 0000-0001-9554-6556
Con StoughCentre for Mental Health and Brain Sciences, Swinburne University, Melbourne 3122, Australia.ORCID 0000-0002-3628-3220

Funding

Kaneka (Japan) 18-002
6 · The paper itself

Abstract

Older age is typically characterized by decrements in cognitive performance relative to younger adults, though it may not necessarily reach clinical impairment. Dietary supplementation with ubiquinol, the reduced form of the antioxidant and cellular energizer CoQ10, may support cognitive function in older individuals. In the current randomized clinical trial of 111 adults aged 60 years and older (ubiquinol, n = 61; placebo, n = 50), 90 days of ubiquinol (200 mg) supplementation resulted in plasma CoQ10 levels being four times that of the placebo group at study end (

Indexed as

agingcardiovascularcognitionCoQ10inflammationoxidative stressubiquinol

Identifiers

PMID42510537
PMCPMC13404211

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.