Evidence mapPaperPMID 42510550Full record

ArticleAntioxidants (Basel, Switzerland)2026

Is Ergothioneine an Important Source of Plasma Trimethylamine

Irwin K Cheah, Lik Hang Wu, Richard M Y Tang, Ulrike Rieprecht, Leroy Sivappiragasam Pakkiri, Arthur Mark Richards, Chester Lee Drum, Barry Halliwell

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irwin K CheahNeurobiology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore.ORCID 0000-0001-9817-468X
Lik Hang WuCardiovascular Research Institute, National University Health System, Singapore 117599, Singapore.ORCID 0000-0002-9642-2552
Richard M Y TangNeurobiology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore.
Ulrike RieprechtNeurobiology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore.
Leroy Sivappiragasam PakkiriCardiovascular Research Institute, National University Health System, Singapore 117599, Singapore.ORCID 0000-0003-2768-0918
Arthur Mark RichardsCardiovascular Research Institute, National University Health System, Singapore 117599, Singapore.
Chester Lee DrumCardiovascular Research Institute, National University Health System, Singapore 117599, Singapore.ORCID 0000-0001-6327-4584
Barry HalliwellNeurobiology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore.ORCID 0000-0002-3560-7123

Funding

Human Health and Potential Industry Alignment Fund Prepositioning Programme H24J4a0143Ministry of Education NUHSRO/2025/057/T1National Medical Research Council OFYIRG22jul-0027
6 · The paper itself

Abstract

High circulating levels of trimethylamine-

Indexed as

ergothionaseergothioneinegut microbiotaneurodegenerationtrimethylaminetrimethylamine-N-oxide

Identifiers

PMID42510550
PMCPMC13405746

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.