ArticleAntioxidants (Basel, Switzerland)2026
Extraction Strategy and C18 Solid-Phase Fractionation Shape Phenolic Profiles, Antioxidant Capacity, and Cancer Cell Antiproliferative Activity of Selected Medicinal Plants.
Domantas Armonavičius, Audrius Maruška, Kristina Bimbiraitė-Survilienė, Mantas Stankevičius, Baltramiejus Jakštys, Tomas Drevinskas, Ugnė Gabrytė, Elżbieta Skrzydlewska, Ona Ragažinskienė, Vilma Kaškonienė and 3 more
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In one paragraphArticle in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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5 · Who and what moneyAuthors and funding
13 authors.
Domantas ArmonavičiusInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.ORCID 0009-0006-0927-6830 Audrius MaruškaInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.ORCID 0000-0002-9267-3805 Kristina Bimbiraitė-SurvilienėInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.
Mantas StankevičiusInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.
Baltramiejus JakštysResearch on Delivery of Medicine and Genes Cluster, Faculty of Natural Sciences, Vytautas Magnus University, LT-44001 Akademija, Kauno Rajonas, Lithuania.ORCID 0000-0002-6106-330X Tomas DrevinskasInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.ORCID 0000-0002-6932-1457 Ugnė GabrytėInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.
Elżbieta SkrzydlewskaDepartment of Analytical Chemistry, Medical University of Białystok, 15-222 Białystok, Poland.
Ona RagažinskienėBotanical Garden, Vytautas Magnus University, LT-46324 Kaunas, Lithuania.
Vilma KaškonienėInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.ORCID 0000-0002-1939-9408 Saulius ŠatkauskasResearch on Delivery of Medicine and Genes Cluster, Faculty of Natural Sciences, Vytautas Magnus University, LT-44001 Akademija, Kauno Rajonas, Lithuania.ORCID 0000-0002-9001-7767 Inga PečiulienėInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.ORCID 0009-0006-1449-9297 Arvydas KanopkaInstrumental Analysis Open Access Centre, Faculty of Natural Sciences, Vytautas Magnus University, Universiteto St. 10, LT-53361 Akademija, Kauno Rajonas, Lithuania.
Funding
: Research was partially supported by the Polish National Agency for Academic Exchange (NAWA) Modern analytically-biomedical platform focused on innovation and creativity in the search for compounds of natural origin with protective and regenerative effects on human skin.
6 · The paper itselfAbstract
Medicinal plants are a rich source of biologically active compounds, including phenolic acids, flavonoids, ellagitannins and other secondary metabolites. However, the contribution of specific groups of phenolic compounds to antiproliferative activity remains insufficiently clarified. This study extends our previous crude-extract screening by evaluating whether C18 solid-phase extraction (SPE) fractions with different phenolic profiles are associated with different antiproliferative responses. In parallel, extraction strategies were compared to assess method-dependent changes in phenolic recovery and antioxidant capacity, and an additional single-species vegetation-stage analysis of
Indexed as
antioxidant activityantiproliferative activitymedicinal plantsphenolic compoundsphenolic profilingsolid-phase extractionvegetation stage
Identifiers
PMID42510601
PMCPMC13404603
What Socratic holds
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